RESEARCH FUNDING (2013-2014)
Bear Necessities Pediatric Cancer Foundation is proud to have collaborated funding with The Rally Foundation and the Jane C. Ventura Charitable Trust to strive towards the goal of finding a cure for the kids.
Children’s Oncology Group
Funded Project: EveryChild which is focused on capturing the biology and outcome on every child diagnosed with cancer in the US and thus being a valuable resource for researchers around the world.
Dana-Farber Cancer Institute
Funded a study to test the use of anti-Ewing chemotherapy and other targeted agents in combination with FAK inhibition to identify promising combination therapy for Ewing Sarcoma.
Funded a Diffuse Intrinsic Pontine Gliomas (DIPGs) study to investigate molecular consequences of the H3F3A mutation, and to evaluate a specific therapeutic for treating these tumors.
Funded an ALL study focusing on children with Down’s syndrome and leukemia. Emphasis on the DS group and to understand how DYRK1A works in ALL.
Funded a study on high-grade gliomas and the role that neuronal firing plays in the growth of HGG cells.
Funded a study on inhibiting the function of CREB to find new therapies for the treatment of AML.
Funded a Ewing-Sarcoma study on the effect of the “EWS/FLI-1” gene on another gene in Ewing’s tumors. By targeting the new gene, the goal is to find new therapies over the toxic chemotherapies currently use.
Funded a high grade glioma study that will be analyzing the differences between “mutant” and “corrected” tumor-derived cells to find disease-specific processes that can serve as targets for the development of new therapies.
University of California, San Francisco
Funded a study targeting Ras effector pathways in Juvenile Myelomonocyic Leukemia (JMML).
University of Michigan
Funded an ALL study on the amplification of NOTCH1 signals by ZMIZ1 in T-cell leukemia, to understand how ZMIZ1 works with NOTCH1 to cause cancer.