Bear Discoveries

Each year, medical research grants are awarded nationwide primarily to junior investigative researchers who make meaningful advancements and discoveries toward finding a cure and therapies for various types of pediatric cancer. Without the support of Bear Necessities, these cutting edge researchers stand little of chance of receiving funding, thus minimizing the chance for a break-through.

Bear Necessities has teamed up with the Rally Foundation for Childhood Cancer Research to receive grant LOIs and applications at Proposal Central under the title “A Collaborative Pediatric Cancer Research Awards Program”.

Research Funding From 2014-2015

Barrow Neurological Institute

St. Joseph Medical Center, Phoenix, AZ – Shwetal Mehta, Ph.D. “A synthetic lethal screen for pediatric low grade astrocytoma” ***

Baylor College of Medicine

Houston, TX – Jason Yustein, PhD., M.D. “Dissecting and Targeting the WNT Pathway in Metastatic Osteosarcoma” **

Children’s Hospital Boston

Boston, MA – Wendy London, PhD. “Histologic-related genes for improved treatment assignment in neuroblastoma ALL”

Dana-Farber Cancer Institute

Boston, MA – Loretta Li, M.D. “Identifying Mechanisms of Resistance to Type II JAK2 Inhibitors in B-ALL”*

John Hopkins University

Baltimore, MD – Catherine Albert, M.D. “NF kappa B is a novel therapeutic target in pediatric rhabdomyosarcoma”***

John Hopkins University

Baltimore, MD – David Loeb, Ph.D., M.D. “Circulating Tumor DNA as a Biomarker of Metastasis in Ewing Sarcoma” **

Northwestern University

Chicago, IL – Rintaro Hashizume, Ph.D., M.D. “Targeted inhibition of histone demethylase activity in brainstem glioma” */ ***

Northwestern University

Chicago, IL – John Crispino. Ph.D. “DYRK1A is a novel target in B-cell leukemia” *

Stanford University

Palo Alto, CA – Bryan Mitton, Ph.D., M.D. “The Role of RSK1 in Acute Myelogenous Leukemia” ****

The Regents of the University of Michigan

Ann Arbor, MI – Mark Chiang, Ph.D., M.D. “Direct and selective coregulation of Notch1 by Zmiz1 in T-cell leukemia” *

The University of Chicago

Chicago, IL – Mark Applebaum, M.D. “Identification of Hypoxia Induced Pathways Driving Aggressive neuroblastoma cells”

University of Texas

M.D. Anderson Cancer Center – Houston, TX – William Brugmann, M.D. “Targeting Immune Evasion in Atypical Teratoid Rhabdoid Tumors” *

University of Washingon

Seattle, WA – Eleanor Chen, Ph.D., M.D. “Epigenetic regulation of rhabdomyosarcoma differentiation” *

UT Southwestern Medical Center

Dallas, TX – Theodore Laetsch, M.D. “Maximizing the Therapeutic Impact of CDK4/6 Inhibition in Rhabdomyosarcoma” **

* Funded in collaboration with The Rally Foundation
** Funded in collaboration with The Rally Foundation and Arms Wide Open
*** Funded in collaboration with Flashes of Hope
**** Funded in collaboration with the Ventura Family

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Chicago Headquarters

55 West Wacker Dr, Suite 1100
Chicago, IL 60601

(312) 214-1200

Texas Chapter

Houston, TX